Tick-tock curly-wurly

The tick-tock of the biological clock.

enous at 3 P.M. but have no appetite when suppertime rolls around. You wake up at 4:00 in the morning and cannot get back to sleep. This scenario is familiar to many people who have flown from the East Coast of the U.S. to California, a trip that entails jumping a three-hour time difference. During a weeklong business trip or vacation, your body no sooner acclimatizes to the new schedule than i...

First the Tick, Now the Tock: Intel® Microarchitecture (Nehalem)

Introducing a New Dynamically and Design-Scalable Microarchitecture that Rewrites the Book on Energy Efficiency and Performance Since the introduction of Intel® CoreTM microarchitecture in 2006 and its 2007 45nm enhancements—the Intel Core microarchitecture (Penryn) family of processors—the blistering performance and energy efficiency of Intel® microprocessors have delivered unprecedented capab...

Tick Tock: Building Browser Red Pills from Timing Side Channels

Red pills allow programs to detect if their execution environment is a CPU emulator or a virtual machine. They are used by digital rights management systems and by malware authors. In this paper we study the possibility of browser-based red pills, namely red pills implemented as Javascript that runs in the browser and attempts to detect if the browser is running inside a virtual machine. These ...

Tick tock: time to recognize the kidney clock.

J Am Soc Nephrol 24: 1901–1912, 2013 4. Borges FT, Melo SA, Özdemir BC, Kato N, Revuelta I, Miller CA, Gattone VH 2nd, LeBleu VS, Kalluri R: TGF-b1-containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis. J Am Soc Nephrol 24: 385–392, 2013 5. van Balkom BW, de Jong OG, Smits M, Brummelman J, den Ouden K, de Bree PM, van Eijnd...

Tick tock, doc: the rapid evaluation of acute stroke to direct therapy and improve patient outcome.